CJC-1295 with DAC
Also called CJC1295, DAC:GRF
CJC-1295 is a stabilised copy of your own GHRH - the upstream signal that gives the pituitary permission to release growth hormone.
Studied in people, in small numbers. The ranges below lean mostly on community-reported dosing and results — what people run, and what they say happened.
12,755 posts20 communities
of community reporting analysed for this compound. That is the part you cannot find anywhere else — the trial data below it, you could look up yourself.
- Longevity & anti-aging
- Recovery & injury
The quick answer
CJC-1295 is a stabilised copy of your own GHRH - the upstream signal that gives the pituitary permission to release growth hormone. The DAC version carries a small chemical anchor that lets it ride along on albumin in the blood, which is why it lasts most of a week instead of half an hour.
What it is not
Not growth hormone, and not interchangeable with the no-DAC version despite sharing a name.
Why people use it
🛏️ Steadier sleep across the whole week; 🩹 Recovery that does not dip between doses; 📅 A once- or twice-weekly rhythm people find easy to keep; 💪 Slow body-composition change over months
What people report using
These are ranges other people have reported running. They are here so you can see what has actually been done — they are not medical advice and not a recommendation for you.
People report running this anywhere from 1mg to 2mg, once a week.Where somebody sits in that range depends on what they are using it for and what they are starting from — the low end is a deliberate choice a lot of people make, not a half-hearted version of the high end.
Recovery & anti-aging
- How often
- Once a week
- Route
- subcutaneous
- Where this comes from
- Small human studies
Sleep and recovery over the first few weeks; skin and body composition, where reported, over two to three months.
What to expect, and when
Week 1: sleep and a general sense of easier recovery; puffiness, if it is going to happen, shows up here too. Week 4-8: recovery and soreness. Month 3 onward: body composition, gradual.
Side effects, and what people do about them
Water retention and puffiness in the hands and face is the most reported effect, and it is the main reason people move to the no-DAC version. Tingling or numbness in the fingers turns up in people running it long. A head-rush in the first hour is common and brief.
Go deeper
Open these only if you want them.
How it actually works
A GHRH analogue carrying a Drug Affinity Complex that binds covalently to serum albumin, stretching half-life to roughly six to eight days. The consequence people actually feel: it lifts the baseline that pulses ride on rather than creating a discrete pulse. That is why it is dosed weekly, and why it is paired with a ghrelin-receptor agonist rather than run alone.
More on the evidence
Small human pharmacokinetic studies only.
What people report, in full
The single most important thing the community says about CJC-1295 is that the name means two different things and people constantly conflate them. With DAC it is in you for most of a week; without DAC it is gone in about half an hour. Almost every confused report - "I felt nothing", "I was bloated the entire time" - traces back to somebody buying one and following a protocol written for the other. The DAC version is described as a background rather than an event: people say they sleep better in a general way rather than pointing at a particular night. Because it holds GH slightly raised all week instead of in pulses, the puffiness reports are almost all from DAC users, and the standard community fix is to switch to no-DAC and dose at night. Long-run users describe it as the one you pick if you cannot face daily injections and will accept a little water in exchange.
Worth knowing
The trials are real. They were not asking the question most people are asking when they come looking for this one.
Human trials exist but were run for GH deficiency and pharmacokinetics, not body composition in healthy adults. It raised GH and IGF-1 reliably - that part is solid ground. What that does for a healthy forty-year-old was not the question anyone asked.
Sources and review
Most of what is useful about these compounds comes from people who have used them, not from trials. These are published analyses of what communities reported. We did not read the posts ourselves and we do not claim to.
12,755 posts20 communities
Reports from 2023-01-01 to 2024-05-18
Rosenberg AE, et al. Injuries, Injections, and Internet Forums: A Qualitative Study of Reddit User Perspectives on Peptide Therapy After Orthopaedic Surgery. Sports Health 2026;18(4):901-910.
Qualitative coding. No dose distributions reported.
These references were located by literature search and recorded as the primary sources behind this record. The publishers block automated retrieval, so they are pointers to the right papers rather than quotations we have checked line by line. They are replaced as we read them properly.
Last reviewed 2026-09-08.
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