GHRP-2
Also called pralmorelin
GHRP-2 is a ghrelin-receptor releaser - the same knock on the door as Ipamorelin, delivered harder.
This one has been through full clinical trials and is an approved medicine somewhere in the world. The ranges below are drawn from those trials and from what the community reports using.
- Longevity & anti-aging
- Recovery & injury
The quick answer
GHRP-2 is a ghrelin-receptor releaser - the same knock on the door as Ipamorelin, delivered harder. It produces a bigger GH pulse, and it is less fussy about what else it touches on the way.
What it is not
Not a more selective option than Ipamorelin - it is the opposite trade, taken on purpose.
Why people use it
📈 The strongest pulse of the common releasers; 🍽️ A mild appetite lift, useful when you are trying to eat; 😴 Sleep; 🩹 Recovery
What people report using
These are ranges other people have reported running. They are here so you can see what has actually been done — they are not medical advice and not a recommendation for you.
- How often
- 1–3 times daily
- Route
- subcutaneous
- Evidence for this
- Approved medicine
Deeper sleep early.
What to expect, and when
Week 1-2: hunger, sleep, head-rush after dosing. Week 4-8: recovery. Month 3 onward: composition.
Side effects, and what people do about them
Hunger, mostly settling after a couple of weeks. Water retention. At higher exposure, prolactin-related effects appear in long-run reports. A head-rush after dosing is common.
Go deeper
Open these only if you want them.
How it actually works
A synthetic hexapeptide GHS-R1a agonist. Stronger GH release than Ipamorelin, with a modest rise in cortisol and prolactin at higher exposure and a real appetite effect.
More on the evidence
Used as a diagnostic GH test agent in Japan. Small human data.
The case against
The human work on it was largely diagnostic - GH stimulation testing - rather than treatment.
What people report, in full
GHRP-2 is chosen deliberately by people who want more than Ipamorelin gives them and accept the trade. The community frames the family as a spectrum: GHRP-6 makes you ravenous, GHRP-2 makes you hungry, Ipamorelin does not. People adding size pick 2 or 6 for exactly that reason; people leaning out pick Ipamorelin. Appetite is reported to fade over the first fortnight, which is treated as a known feature rather than a surprise. The advice that repeats most is to run it in defined blocks rather than continuously, because the long-run prolactin reports come from people who never stopped. Dosed away from food, most often at night, like the rest of the family.
Sources and review
https://pubmed.ncbi.nlm.nih.gov/17609397/
Last reviewed 2026-09-08.
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