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Anti-Aging & Longevity

GHRP-2

Also called pralmorelin

GHRP-2 is a ghrelin-receptor releaser - the same knock on the door as Ipamorelin, delivered harder.

Where this answer comes fromApproved medicine

This one has been through full clinical trials and is an approved medicine somewhere in the world. The ranges below are drawn from those trials and from what the community reports using.

Approved as a medicine somewhere

Japan · GHRP Kaken 100 (pralmorelin) · growth hormone deficiency diagnostic

The quick answer

GHRP-2 is a ghrelin-receptor releaser - the same knock on the door as Ipamorelin, delivered harder. It produces a bigger GH pulse, and it is less fussy about what else it touches on the way.

What it is not

Not a more selective option than Ipamorelin - it is the opposite trade, taken on purpose.

Why people use it

📈 The strongest pulse of the common releasers; 🍽️ A mild appetite lift, useful when you are trying to eat; 😴 Sleep; 🩹 Recovery

What people report using

These are ranges other people have reported running. They are here so you can see what has actually been done — they are not medical advice and not a recommendation for you.

Standard — 100mcg, 1–3 times daily100mcg

Recovery & anti-aging

How often
1–3 times daily
Route
subcutaneous
Where this comes from
Approved medicine

Deeper sleep early.

What to expect, and when

Week 1-2: hunger, sleep, head-rush after dosing. Week 4-8: recovery. Month 3 onward: composition.

Side effects, and what people do about them

Hunger, mostly settling after a couple of weeks. Water retention. At higher exposure, prolactin-related effects appear in long-run reports. A head-rush after dosing is common.

Go deeper

Open these only if you want them.

How it actually works

A synthetic hexapeptide GHS-R1a agonist. Stronger GH release than Ipamorelin, with a modest rise in cortisol and prolactin at higher exposure and a real appetite effect.

More on the evidence

Used as a diagnostic GH test agent in Japan. Small human data.

What people report, in full

GHRP-2 is chosen deliberately by people who want more than Ipamorelin gives them and accept the trade. The community frames the family as a spectrum: GHRP-6 makes you ravenous, GHRP-2 makes you hungry, Ipamorelin does not. People adding size pick 2 or 6 for exactly that reason; people leaning out pick Ipamorelin. Appetite is reported to fade over the first fortnight, which is treated as a known feature rather than a surprise. The advice that repeats most is to run it in defined blocks rather than continuously, because the long-run prolactin reports come from people who never stopped. Dosed away from food, most often at night, like the rest of the family.

Worth knowing

The human testing was for a different purpose than people use it for here

The trials are real. They were not asking the question most people are asking when they come looking for this one.

The case against

The human work on it was largely diagnostic - GH stimulation testing - rather than treatment.

Sources and review

What people report

This record is built on what the wider community reports doing and experiencing, summarised above. No counted dataset has been attached to this compound yet — when one is published, it goes here with its numbers.

References

A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency. Eur J Endocrinol 2007;157(1):19. PMID 17609397.Evaluated GHRP-2 as a GH stimulation test for diagnosing adult GH deficiency.

These references were located by literature search and recorded as the primary sources behind this record. The publishers block automated retrieval, so they are pointers to the right papers rather than quotations we have checked line by line. They are replaced as we read them properly.

Last reviewed 2026-09-08.

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