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Anti-Aging & Longevity

CJC-1295 without DAC

Also called Mod GRF 1-29, modified GRF

The same GHRH signal without the albumin anchor - in and out in about half an hour.

Where this answer comes fromSmall human studies

Studied in people, in small numbers. The ranges below lean mostly on community-reported dosing and results — what people run, and what they say happened.

The quick answer

The same GHRH signal without the albumin anchor - in and out in about half an hour. That short window is the point: it produces a pulse shaped like the one your body makes on its own, rather than a raised baseline.

What it is not

Not the DAC version. A protocol written for one does not transfer to the other.

Why people use it

😴 Sleep depth, the most consistent report; 💧 Far less water retention than the DAC version; 🩹 Recovery; 🎯 A pulse pattern closer to the natural one

What people report using

These are ranges other people have reported running. They are here so you can see what has actually been done — they are not medical advice and not a recommendation for you.

Recovery & anti-aging100mcg
How often
1–3 times daily
Route
subcutaneous
Evidence for this
Small human studies

Sleep depth early, recovery over weeks.

What to expect, and when

Week 1-2: sleep, vivid dreams, the evening flush. Week 4-8: recovery. Month 3 onward: composition, modest.

Side effects, and what people do about them

Head fullness in the first minutes. Much less puffiness than DAC. A flush in the face is common in the pairing, and the community explanation for it is the right one: it is a histamine response, not a measure of potency.

Go deeper

Open these only if you want them.

How it actually works

Modified GRF(1-29): a four-substitution GHRH fragment stable enough to survive injection but cleared within roughly thirty minutes. Paired with a ghrelin-receptor agonist it produces a sharp, short GH pulse and then returns to baseline, which is the physiological pattern.

More on the evidence

Short-acting GHRH analogue. Small human PK work.

The case against

Same trial picture as the DAC version - studied for GH deficiency and pharmacokinetics, not for body composition in healthy adults.

What people report, in full

This is the version experienced users converge on, and the reason they give is always the same: pulses, not a plateau. People who ran DAC and moved across describe the water coming off within a week or two while the sleep effect stayed. It is dosed at night on an empty stomach, and the empty stomach is not a nicety - the recurring failure story is someone dosing after a meal and concluding the vial was fake. Almost nobody runs it alone; it is the CJC half of the CJC-plus-Ipamorelin pairing and the discussion treats that pair as one thing. The face flush comes up constantly and the community handles it well: histamine, a few minutes, not a sign of strength.

Sources and review

References

https://pubmed.ncbi.nlm.nih.gov/8329825/

Last reviewed 2026-09-08.

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